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What is the difference between Xeljanz and Xeljanz XR?
If you have an autoimmune disorder, your doctor may prescribe Xeljanz or Xeljanz XR. These prescription drugs are used to treat the following conditions in adults when other treatments have failed:
ulcerative colitis, moderate to severe
Psoriatic arthritis, moderate to severe rheumatoid arthritis
Xeljanz and Xeljanz XR are tablets that are taken orally. Xeljanz XR is a long-acting version of the drug Xeljanz.
Xeljanz is also available as an oral solution to be taken by mouth. It is given to some children who have a type of juvenile idiopathic arthritis.
To learn more about how Xeljanz and Xeljanz XR are used, see the section below titled “What are Xeljanz and Xeljanz XR used for?”
Tofacitinib is the active ingredient in Xeljanz and Xeljanz XR. Tofacitinib is not available in a generic form. Instead, it is only available as the brand-name medications Xeljanz and Xeljanz XR.
This article will go over the side effects, cost, and other aspects of Xeljanz and Xeljanz XR.
What are the side effects of Xeljanz and Xeljanz XR?
Xeljanz and Xeljanz XR, like most medications, can cause mild to severe side effects. The following are some of the more common side effects of Xeljanz and Xeljanz XR. These lists do not include all of the potential side effects.
More information about the potential side effects of Xeljanz and Xeljanz XR can be obtained from your doctor or pharmacist. They can also recommend ways to reduce side effects.
Side effects are minor.
Here is a list of some of the less serious side effects that Xeljanz and Xeljanz XR can cause. Talk to your doctor or pharmacist about other minor side effects, or read the medication guide for Xeljanz and Xeljanz XR.
Mild Xeljanz and Xeljanz XR side effects may include:
Upper respiratory tract infection, including the common cold, headache* rash* diarrhea high blood pressure
Mild side effects of many drugs may disappear within a few days or weeks. However, if they become bothersome, consult your doctor or pharmacist.
* See the “Side effect focus” section below for more information on this side effect.
Severe side effects
Serious side effects of Xeljanz and Xeljanz XR are possible, but they are uncommon. Call your doctor right away if you experience serious side effects from Xeljanz or Xeljanz XR. If you believe you are in a medical emergency, call 911 or your local emergency number.
Severe side effects may include:
Anemia is a type of blood disorder (low level of red blood cells)
Boxed cautions: clots in the blood, serious infections, and certain cancers * an allergic reaction* See the “Side effect focus” section below for more information on these side effects.
emphasis on side effects
Learn more about some of the potential side effects of Xeljanz and Xeljanz XR.
Warnings in boxes
Blood clots, serious infection, and certain cancers are all mentioned in the boxed warning for Xeljanz and Xeljanz XR. A boxed caution The Food and Drug Administration has issued a serious warning called Trusted Source (FDA).
Infections that are serious. Xeljanz and Xeljanz XR may increase your chances of getting a serious infection. This risk is increased if you also take other immunosuppressive medications, such as corticosteroids or methotrexate. Immunosuppressive medications reduce your body’s ability to fight infections. (Xeljanz and Xeljanz XR are also immunosuppressive medications.)
Infections reported in Xeljanz or Xeljanz XR users included bacterial infections, fungal infections, and viral infections such as herpes zoster (shingles). There were also reports of flare-ups of previous infections such as tuberculosis (TB), hepatitis B, and hepatitis C.
Pneumonia, skin infection, and urinary tract infection were the most commonly reported infections with Xeljanz and Xeljanz XR (UTI).
Infection symptoms can vary, but they may include:
Chills or fever
cough exhaustion (lack of energy)
rash and muscle aches
Clots of blood form. If you are 50 or older, have rheumatoid arthritis, and have at least one risk factor* for heart disease, Xeljanz and Xeljanz XR may increase your risk of blood clots. This includes clots like:
pulmonary embolism (blood clot in your lungs)
thrombosis of the arteries (blood clot in an artery)
deep vein thrombosis (blood clot in a vein)
Xeljanz and Xeljanz XR can also increase the risk of death in this case.
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These risks were higher in studies with a 10 mg dose of Xeljanz taken twice daily compared to lower doses of Xeljanz.
Blood clot symptoms can include:
pain in your chest pain in your arm or leg
Swelling in your arm or leg difficulty breathing * High blood pressure, high cholesterol, or obesity are all risk factors for heart disease. Smoking is also a risk factor for cardiovascular disease.
Cancer, as well as immune system issues. Xeljanz and Xeljanz XR can increase your risk of developing certain cancers.
Several types of cancer have been reported in Xeljanz studies, including:
cancerous lymphoma (cancer in your lymphatic system)
cancer of the lungs
cancer of the colon
cancer of the stomach
cancer of the prostate
Renal cell carcinoma (a type of kidney cancer)
melanoma that is malignant (a type of skin cancer)
Among the cancer symptoms are:
Mole changes or other skin changes
exhaustion (lack of energy)
weight loss that is unexplained
Cancer risk was also higher in people taking Xeljanz who had had a kidney transplant and were taking other immunosuppressant drugs. Furthermore, certain people who take Xeljanz with kidney transplant rejection drugs may be at an increased risk of reactivation of certain immune system viruses, such as the Epstein-Barr virus.
What might be of assistance
Before you start taking Xeljanz or Xeljanz XR, your doctor will order blood tests to check for infection. If you have an infection, your doctor may advise you to delay starting Xeljanz or Xeljanz XR until the infection is treated. They’ll also keep an eye out for infections while you’re taking Xeljanz or Xeljanz XR, as well as for a while after you stop taking it.
You should not take Xeljanz or Xeljanz XR if you have heart disease or a history of blood clots. If you develop blood clots while on treatment, your doctor will instruct you to stop taking the drug and will monitor you to see if you require treatment for your blood clots.
Inquire with your doctor about all of the risks and benefits of Xeljanz or Xeljanz XR, including the possibility of cancer and immune system problems. Share your medical history and inform your doctor if you have had cancer in the past or are currently undergoing cancer treatment.
Some people who take Xeljanz or Xeljanz XR may get a rash. During the studies, this was a common side effect of the drugs.
When previous infections in your body resurface, it is possible to develop a rash. For example, the chickenpox virus can cause shingles in your body, which is a serious side effect of Xeljanz and Xeljanz XR. A rash may also occur as a result of an allergic reaction to Xeljanz or Xeljanz XR.
What might be of assistance
If you develop a rash while taking Xeljanz or Xeljanz XR, contact your doctor immediately. Your rash could indicate a recurrence of a previous infection or an allergic reaction.
Your doctor will examine you to determine the type of rash you have. And they’ll advise you on the best course of action.
A common side effect of Xeljanz and Xeljanz XR is headache. In studies, people taking Xeljanz twice a day for ulcerative colitis (UC) experienced more headaches than those taking the drug for one of its other approved uses.
What might be of assistance
Keep a record of any headaches you experience while taking Xeljanz or Xeljanz XR. This can assist your doctor in learning more about what is causing your headaches.
If necessary, your doctor can recommend a safe and effective treatment to help relieve your headache. However, do not take pain relievers without first consulting your doctor or pharmacist.
REACTIONS TO ALLERGENS
Xeljanz and Xeljanz XR may cause an allergic reaction in some people.
Mild allergic reactions can cause the following symptoms:
Itching from a skin rash
A more severe allergic reaction, such as flushing (warmth, swelling, redness, or discoloration of your skin), is uncommon but possible. Swelling under your skin, usually in your eyelids, lips, hands, or feet, is one of the symptoms of a severe allergic reaction. They may also include swelling of your tongue, mouth, or throat, which can make breathing difficult.
If you have an allergic reaction to Xeljanz or Xeljanz XR, contact your doctor right away. However, if you believe you are experiencing a medical emergency, dial 911 or your local emergency number.
What are the prices of Xeljanz and Xeljanz XR?
Prescription drug prices can vary greatly depending on a variety of factors. These considerations include what your insurance policy covers and which pharmacy you use. Visit GoodRx.com to find the most recent Xeljanz and Xeljanz XR prices in your area.
Speak with your doctor or pharmacist if you have any questions about how to pay for your prescription. You can also check the manufacturer’s website for the Xeljanz and Xeljanz XR to see if there are any support options.
What are some frequently asked Xeljanz and Xeljanz XR questions?
Find out the answers to some of the most frequently asked questions about Xeljanz and Xeljanz XR.
Can Xeljanz or Xeljanz XR be used to treat alopecia areata?
No, these medications have not been approved to treat alopecia or alopecia areata. Alopecia is also known as hair loss. Alopecia areata causes hair loss in small patches.
Doctors may prescribe Xeljanz or Xeljanz XR for this purpose off-label. Off-label use is when a drug is used for a purpose other than what it was approved for.
According to Trusted Source, tofacitinib (the active ingredient in Xeljanz and Xeljanz XR) may be effective for treating hair loss. People who stopped taking tofacitinib had hair shedding within 4 to 5 weeks of stopping the drug.
Speak with your doctor if you want to learn more about using Xeljanz or Xeljanz XR for hair loss. They can assist you in learning more about the risks and benefits of treatment. Keep in mind, however, that off-label use of Xeljanz or Xeljanz XR may not be covered by your insurance.
Do Xeljanz and Xeljanz XR result in weight gain or loss?
No, Xeljanz and Xeljanz XR do not cause weight gain or loss. However, serious side effects of these medications, or your condition itself, may result in unexplained weight loss.
Weight loss, for example, can occur as a result of diarrhea, a serious infection, or cancer. These side effects are also possible with Xeljanz and Xeljanz XR. (See the section above titled “What are the side effects of Xeljanz and Xeljanz XR?” for more information on serious infection and cancer risks.)
Other medications you’re taking for your condition may also cause weight changes.
It’s critical to notify your doctor if you notice any changes in your appetite or body weight while taking Xeljanz. Your doctor will order tests to ensure that you are not experiencing any serious side effects from your treatment. And your doctor can advise you on how to maintain a healthy body weight.
How do Xeljanz and Xeljanz XR stack up against Rinvoq?
Xeljanz, Xeljanz XR, and Rinvoq are all members of the same class of drugs known as Janus kinase (JAK) inhibitors. This means they have some similarities in their applications and side effects. They do, however, differ in some ways.
Tofacitinib is the active drug in Xeljanz and Xeljanz XR, while upadacitinib is the active drug in Rinvoq.
Xeljanz, Xeljanz XR, and Rinvoq have all been approved to treat rheumatoid arthritis in adults when other medications have failed.
However, Xeljanz and Xeljanz XR have additional applications. Adults can use Xeljanz and Xeljanz XR to treat ulcerative colitis and psoriatic arthritis. In addition, Xeljanz is approved for the treatment of a type of juvenile idiopathic arthritis in some children.
Xeljanz, Xeljanz XR, and Rinvoq all have serious side effects. See the section above titled “What are the side effects of Xeljanz and Xeljanz XR?” for more information. See the Rinvoq medication guide for more information on the drug’s side effects.
Speak with your doctor if you want to learn more about these medications.
What is the purpose of Xeljanz and Xeljanz XR?
Your doctor may prescribe Xeljanz or Xeljanz XR if you have certain autoimmune conditions. These prescription medications are used by adults as well as some children.
In adults, Xeljanz and Xeljanz XR are used to treat:
Ulcerative colitis can range from mild to severe (UC). When another type of drug called a tumor necrosis factor (TNF) blocker did not work or caused bothersome side effects, Xeljanz or Xeljanz XR is prescribed for UC. Adalimumab is an example of a TNF blocker (Humira). You have inflammation in your digestive tract if you have UC. This can result in abdominal pain and irregular bowel movements.
Rheumatoid arthritis, moderate to severe (RA). When methotrexate did not work or caused bothersome side effects, Xeljanz or Xeljanz XR is prescribed for RA. With RA, you may experience joint pain, swelling, and deformities.
Arthritis psoriatica (PsA). When methotrexate or other disease-modifying antirheumatic drugs (DMARDs) did not work or caused bothersome side effects, Xeljanz or Xeljanz XR is prescribed for PsA. You have pain and swelling in your joints if you have PsA. You can also have pink or darker patches of skin that may become scaley in appearance.
Furthermore, Xeljanz oral solution can be prescribed for children aged 2 and up who have polyarticular juvenile idiopathic arthritis. This is a form of arthritis that affects children. And because it is polyarticular, it affects many joints throughout their body.
In autoimmune diseases, your immune system attacks and inflames tissues in your own body. Xeljanz and Xeljanz XR treat certain autoimmune conditions by inhibiting inflammatory responses within the body.
It should be noted that Xeljanz and Xeljanz XR should not be used in conjunction with other strong immunosuppressive medications. Azathioprine and cyclosporine are examples of such medications. Furthermore, Xeljanz and Xeljanz XR should not be combined with biologic DMARDs. Discuss with your doctor which medications are compatible with Xeljanz or Xeljanz XR.
What are the reactions to Xeljanz and Xeljanz XR?
Your doctor will tell you how to take Xeljanz or Xeljanz XR. They’ll also tell you how much to take and how frequently. Make sure to follow your doctor’s advice.
In general, you’ll begin with the lowest possible dose of Xeljanz or Xeljanz XR, and your doctor will monitor your progress. If necessary, your doctor may adjust your dosage. However, this will be dependent on how well the treatment is working to manage your condition.
The dosages listed below are common, but always follow your doctor’s instructions.
Taking Xeljanz and Xeljanz XR as examples
Xeljanz and Xeljanz XR are tablets that are taken orally.
Xeljanz is an immediate-release version of the drug, which means it enters your body all at once when you take it. Xeljanz XR is a long-acting version of the drug Xeljanz. It is gradually released into your body after you have taken it.
Xeljanz is also available in a solution that can be taken orally by children.
Xeljanz or Xeljanz XR can be taken at any time of day. There is no best time of day to take it. To avoid missing doses, try to take the medication at the same time every day.
If your doctor has prescribed Xeljanz twice a day, take them 12 hours apart, once in the morning and once in the evening.
The frequency with which you take Xeljanz or Xeljanz XR depends on your condition and the type of drug prescribed by your doctor. As an example:
Xeljanz can be taken twice daily.
Xeljanz XR can be taken once daily.
Your doctor will recommend the appropriate dosage for you based on the following factors:
medical conditions related to your age You may be taking additional medications.
Your Xeljanz dose may be adjusted in some cases based on your liver or kidney function.
Combining Xeljanz and Xeljanz XR with other medications
Your doctor may prescribe Xeljanz or Xeljanz XR in conjunction with other medications. For example, if Xeljanz isn’t managing your symptoms on its own, your doctor may add another medication to help improve your treatment.
Other drugs that may be combined with Xeljanz or Xeljanz XR include:
Methotrexate, prednisone, hydroxychloroquine (Plaquenil), leflunomide (Arava), and sulfasalazine are all examples of medications (Azulfidine)
Concerns about using Xeljanz and Xeljanz XR
Below, we address some frequently asked questions about taking Xeljanz or Xeljanz XR.
What if I forget to take Xeljanz or Xeljanz XR? As soon as you remember, take the missed dose. However, if it is close to the time you will take your next dose, do not take two doses at the same time. Simply take your next scheduled dose as usual. Also, consider setting a reminder to help you remember to take your doses on a regular basis.
Will I have to use Xeljanz and Xeljanz XR in the long run? As long as the medication is effectively managing your symptoms, your doctor may instruct you to continue taking it on a regular basis. Consult your doctor to see if taking Xeljanz or Xeljanz XR on a long-term basis is right for you.
Xeljanz and Xeljanz XR can they be chewed, crushed, or split? Xeljanz (immediate-release) tablets may be crushed or chewed. Xeljanz XR (extended-release) tablets, on the other hand, should not be split, crushed, or chewed. This has the potential to change how they function. If you have difficulty swallowing pills, speak with your pharmacist or doctor about alternative options.
Is it safe to take Xeljanz and Xeljanz XR with food? Food has no effect on how Xeljanz and Xeljanz XR work. You can therefore take Xeljanz or Xeljanz XR with or without food.
How long does it take Xeljanz and Xeljanz XR to work? Xeljanz and Xeljanz XR begin working immediately after you take a dose. However, keep in mind that it may take a few weeks for your symptoms to improve. Inquire with your doctor about when you can expect to see Xeljanz relieve your symptoms. When you begin taking the medication, your doctor will monitor you to ensure that it is effective.
YOUR DOCTOR’S QUESTIONS
You may have concerns about Xeljanz and Xeljanz XR, as well as your treatment plan. It is critical that you discuss all of your concerns with your doctor.
Here are a few pointers to help you with your discussion:
Write down questions like, “How will Xeljanz and Xeljanz XR affect my body, mood, or lifestyle?” before your appointment.
Bring someone with you to your appointment if it will make you feel more at ease.
If you have any questions about your condition or treatment, ask your doctor to explain it to you.
Remember that your doctor and other healthcare providers are there to assist you. And they want you to receive the best possible care. As a result, don’t be afraid to ask questions or provide feedback on your treatment.
What should you think about before taking Xeljanz or Xeljanz XR?
Discuss any medical conditions you have with your doctor before beginning treatment with Xeljanz or Xeljanz XR.
If you have kidney or liver problems, your doctor may perform tests to see how well your liver and kidneys are working. Your Xeljanz dose may be adjusted in some cases based on your liver or kidney function.
Also, notify your doctor if you:
have any infections or a weakened immune system suffer from heart or lung problems
if you have HIV, hepatitis B or C, or shingles
have a history of blood clots have stomach or intestine pain, diverticulitis, or ulcers received a vaccine recently or are scheduled to receive a vaccine are pregnant, planning to become pregnant, or breastfeeding
Also, inform your doctor about any medications or supplements you’re using.
The risks and precautions of using Xeljanz or Xeljanz XR are described below.
Medication interactions can occur with other medications, vaccines, and even foods. This can affect how effective or safe the medication is for you.
Before taking Xeljanz or Xeljanz XR, inform your doctor about all medications you are currently taking (including prescription and over-the-counter types). Describe any vitamins, herbs, or supplements you use as well. Your doctor or pharmacist can advise you on any possible interactions between these medications and Xeljanz and Xeljanz XR.
Please keep in mind that the lists below do not include all of the drugs that may interact with Xeljanz and Xeljanz XR. Your doctor or pharmacist can tell you more about these and other possible interactions with Xeljanz and Xeljanz XR.
Drug or supplement interactions
Xeljanz and Xeljanz XR can interact with a variety of medications. More information about these interactions can be obtained from your doctor or pharmacist.
Interactions between Xeljanz and Xeljanz XR medications can either increase or decrease the effects of the drugs.
Certain drugs, for example, slow the removal of Xeljanz and Xeljanz XR from your body. And this can increase your chances of experiencing side effects from Xeljanz and Xeljanz XR. These are some examples of these drugs:
clarithromycin is an antibiotic (Biaxin)
fluconazole, an antifungal (Diflucan)
Some drugs, on the other hand, can hasten the removal of Xeljanz and Xeljanz XR from your body. As a result, Xeljanz and Xeljanz XR may be less effective for your condition. Here are a few examples of these types of drugs:
Rifampin is an antibiotic.
the HIV medication efavirenz the seizure medications phenytoin and carbamazepine
Immunosuppressive drug interactions
When combined with other immunosuppressive medications, Xeljanz and Xeljanz XR may increase the risk of serious infection. (Immunosuppressive medications reduce your body’s ability to fight infections.)
Immunosuppressive medications include:
azathioprine adalimumab (Humira) (Imuran)
the antibiotic cyclosporine (Neoral)
Infliximab (Enbrel) etanercept (Enbrel) golimumab (Simponi) (Remicade)
Warnings in boxes
For the risks of certain health conditions, Xeljanz and Xeljanz XR have boxed warningsTrusted Source. A boxed warning from the Food and Drug Administration is a serious warning (FDA). These precautions are detailed below.
Infections that are serious. Taking Xeljanz or Xeljanz XR may increase your chances of getting a serious infection. Taking either medication may increase your chances of getting serious bacterial, viral, or fungal infections.
Clots of blood form. If you are 50 or older, have rheumatoid arthritis, and have at least one risk factor for heart disease, Xeljanz may increase your risk of blood clots. Clots such as pulmonary embolism (blood clot in the lungs), arterial thrombosis (blood clot in an artery), and deep venous thrombosis are examples of this (blood clot in a vein). Xeljanz and Xeljanz XR can also increase the risk of death in this case.
Cancer, as well as immune system issues. Xeljanz and Xeljanz XR have been linked to an increased risk of certain cancers, including lymphoma (cancer in your lymphatic system). These medications may also increase the risk of immune system disorders in some people.
If you want to learn more about these boxed warnings, go to the “What are the side effects of Xeljanz and Xeljanz XR?” section.
If you have certain medical conditions or other factors that affect your health, Xeljanz and Xeljanz XR may not be right for you. Before taking Xeljanz or Xeljanz XR, discuss your medical history with your doctor. Among the factors to consider are those listed below.
Problems with the gastrointestinal tract (GI). Xeljanz and Xeljanz XR can have serious side effects on your digestive tract. Tears in your stomach and small or large intestine are examples of such issues. This risk is increased for people who take other drugs with GI side effects, such as nonsteroidal anti-inflammatory drugs (NSAIDs). Inquire with your doctor for more information about the risks of GI problems with Xeljanz or Xeljanz XR.
Problems with the liver. If you have liver issues, your doctor may adjust your Xeljanz or Xeljanz XR dosage. They will also monitor your liver while you are taking either drug. If you have a serious liver condition, such as hepatitis B or C, consult your doctor to see if Xeljanz or Xeljanz XR is appropriate for you.
An allergic reaction occurs. You should not take Xeljanz or Xeljanz XR if you have had an allergic reaction to Xeljanz or any of its ingredients. Inquire with your doctor about other medications that may be a better fit for you.
When combined with alcohol
Drinking alcohol can increase your chances of developing liver problems. Furthermore, Xeljanz and Xeljanz XR may impair liver function in some people. The drugs can also cause an increase in the levels of liver enzymes.
This risk may be increased if Xeljanz or Xeljanz XR is combined with certain other immunosuppressive medications. (Immunosuppressive medications reduce your body’s ability to fight infections.)
Check with your doctor to see if you can drink alcohol while taking Xeljanz or Xeljanz XR. Your doctor may order liver function tests to determine how well your liver is functioning before and while you are taking Xeljanz.
Breastfeeding and pregnancy
It is unknown whether Xeljanz or Xeljanz XR is safe to take while pregnant. Inquire with your doctor about the risks and benefits of using either medication during pregnancy.
If you’ve taken Xeljanz or Xeljanz XR while pregnant or intend to do so, ask your doctor about the Xeljanz pregnancy registry. You can also learn more about it by visiting the registry’s website or calling 877-311-8972.
Furthermore, Xeljanz and Xeljanz XR may impair your ability to become pregnant while you are taking them or after you have stopped taking them. Before beginning this treatment, discuss your reproductive desires with your doctor.
Because Xeljanz and Xeljanz XR may pass into breast milk, they should not be used if you are breastfeeding. Inquire with your doctor about the risks of using either drug while breastfeeding.
What should be done in the event of an overdose?
Take no more Xeljanz or Xeljanz XR than your doctor has prescribed. Using more than this amount can result in serious side effects such as liver or kidney damage and gastrointestinal perforation. (Gastrointestinal perforation is a tear in the stomach or intestines.)
What should you do if you take too much Xeljanz or Xeljanz XR?
If you believe you have taken too much Xeljanz or Xeljanz XR, contact your doctor. You can also contact the American Association of Poison Control Centers by calling 800-222-1222 or visiting their website. If you have severe symptoms, call 911 (or your local emergency number) or go to the nearest emergency room right away.
What questions should you ask your doctor
Xeljanz and Xeljanz XR are prescription medications used to treat autoimmune diseases. These medications are used when other medications have failed. They can also be taken alone or in conjunction with other medications.
Before beginning Xeljanz or Xeljanz XR, consult with your doctor about alternative treatments for:
A type of inflammatory bowel disease is ulcerative colitis (IBD)
Psoriatic arthritis rheumatoid arthritis
In addition, ask your doctor what to expect from Xeljanz or Xeljanz XR treatment. To get you started, here are a few questions:
What can I do to reduce my infection risk while taking Xeljanz or Xeljanz XR?
Will Xeljanz or Xeljanz XR alleviate my pain?
If I have a cold, can I take Xeljanz or Xeljanz XR?
Sign up for Healthline’s newsletters on psoriasis, rheumatoid arthritis, and IBD to learn more about these conditions.
Q: Can I take ibuprofen (Advil) along with Xeljanz?
Patient A (anonymous):
Ibuprofen (Advil) should not be taken with Xeljanz or Xeljanz XR.
Although there is no interaction between the medications, each increases your risk of gastrointestinal perforations. (A gastrointestinal perforation is a tear in the stomach or intestines.)
As a result, taking ibuprofen alongside Xeljanz or Xeljanz XR may increase your risk of perforation.
Talk to your doctor if you need additional pain relief for your symptoms while taking Xeljanz or Xeljanz XR. They might alter your current treatment plan. Also, before taking any medications with Xeljanz or Xeljanz XR, consult your doctor or pharmacist.
Answers by Dena Westphalen, PharmD reflect the views of our medical experts. All content is strictly for informational purposes only and should not be construed as medical advice.
Disclaimer: Healthline has made every effort to ensure that all information is accurate, complete, and up to date. This article, however, should not be used to replace the knowledge and expertise of a licensed healthcare professional. Before taking any medication, you should always consult your doctor or another healthcare professional. The drug information contained in this publication is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The lack of warnings or other information for a particular drug does not imply that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.