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Xzampta used to alleviate severe ongoing pain (such as due to cancer). Oxycodone is an opioid analgesic, which is a type of pain reliever. It changes how your body feels and responds to pain by acting on the brain. Higher doses of this drug (more than 36 milligrams per dose or 72 milligrams per day) should be used only if you have been taking a moderate to high dose of an opioid medication on a regular basis. If these doses are taken by someone who has not been taking opioids on a regular basis, they may result in an overdose (or even death). Use the extended-release form of oxycodone only for minor pain that will go away in a few days. This medication should not be used on an as-needed basis.
How to Apply Xzampta
Also see the Warning section.
Before you begin taking extended-release oxycodone, and each time you get a refill, read the Medication Guide provided by your pharmacist. If you have any concerns, consult your doctor or pharmacist.
Take this medication on a regular basis, as directed by your doctor, rather than only when you are experiencing severe (breakthrough) pain. Take this medication with food every 12 hours. Because food can influence the amount of drug absorbed, take this medication with the same amount of food each time. If you have nausea, speak with your doctor or pharmacist about ways to alleviate it (such as lying down for 1 to 2 hours with as little head movement as possible).
Take the capsules whole. The capsules should not be crushed or chewed.
If you have difficulty swallowing the capsules, open them and sprinkle the contents on a spoonful of soft food (such as applesauce, yogurt). Without chewing, immediately swallow the entire drug/food mixture. Then, rinse your mouth with water and swallow the rinse liquid to ensure that you have swallowed the entire dose. Do not chew the mixture or make a supply ahead of time. Another method is to open the capsule and sprinkle the contents into a cup. Then, directly into your mouth, pour the contents, and swallow.
If your doctor or pharmacist tells you that you can eat grapefruit or drink grapefruit juice while taking this medication, do so. Grapefruit can increase the likelihood of side effects when taking this medication. For more information, consult your doctor or pharmacist.
The dosage is determined by your medical condition as well as your response to treatment. Do not increase your dose or use this medication more frequently or for a longer period of time than prescribed, as this may increase your risk of side effects. When instructed, discontinue the medication.
Before you begin taking this medication, consult with your doctor or pharmacist to see if you should discontinue or modify your use of any other opioid medications (s). Other pain relievers (such as acetaminophen and ibuprofen) may be prescribed as well. Inquire with your doctor or pharmacist about using oxycodone safely with other medications.
Stopping this medication abruptly may cause withdrawal symptoms, especially if you have been taking it for a long time or in high doses. To avoid withdrawal, your doctor may gradually reduce your dose. Notify your doctor or pharmacist right away if you experience any withdrawal symptoms such as restlessness, mental/mood changes (including anxiety, difficulty sleeping, or suicidal thoughts), watering eyes, runny nose, nausea, diarrhea, sweating, muscle aches, or sudden behavioral changes.
When Xzampta is used for an extended period of time, it may lose its effectiveness. Consult your doctor if this medication is no longer working properly.
Despite the fact that it benefits many people, Xzampta can sometimes lead to addiction. If you have a substance use disorder (such as overuse or addiction to drugs/alcohol), your risk may be increased. To reduce the risk of addiction, take this medication exactly as directed. For more information, consult your doctor or pharmacist.
Inform your doctor if your pain does not improve or worsens.
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